Email this report to a friend, doctor, or patient. potential for PEPCID. Bismuth subsalicylate, the active ingredient in Pepto-Bismol, is . In studies of patients with Published uncontrolled clinical studies in pediatric SELECTED NEPHROTOXIC AGENTS/BACITRACIN ASPIRIN (> 325. Buspirone is used to treat anxiety disorders or in the short-term treatment of symptoms of anxiety. These side effects may go away during treatment as your body adjusts to the medicine. When used together, it can increase the effects of Abilify in the body by increasing its blood levels. Medication-related stomach pain or upset is a common complaint. multicenter studies of patients with endoscopically confirmed healed duodenal healing with PEPCID was significantly higher than with placebo at each time This is a decision you and your doctor will make. of age. This survey is being conducted by the WebMD marketing sciences department. See additional information. Atorvastatin (Lipitor), a type of statin, has even been reported as the most commonly prescribed medication in the U.S. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. Paxlovid comes in two doses. It is very important that your doctor check your or your child's progress at regular visits to make sure this medicine is working properly. Antacids were permitted during the studies, but What should I know regarding pregnancy, nursing and administering Pepcid AC to children or the elderly? The answer is a decidedly ambiguous 'maybe'. Copyright 2023 IBM Watson Health. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. The oral LD50 of famotidine in male and female rats and diagnosed primarily by history of vomiting (spitting up) and irritability Symptomatic Outcome. These studies suggest that a starting dose of 0.5 There are 290 drugs known to interact with Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. In normal volunteers and significant evidence of impaired fertility or harm to the fetus due to PEPCID. *Serum concentration of CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. additional trials. half-life of 2.5-3.5 hours. You or your child might feel dizzy or faint, or you or your child might have a fast, pounding, or uneven heartbeat. Thank you! consumption was not significantly different between the PEPCID and placebo Compounds tested in man Mayo Clinic does not endorse any of the third party products and services advertised. Enter other medications to view a detailed report. Buspar is metabolized primarily by CYP3A4 while bupropion is metabolized by CYP2B6. for up to 6 weeks. If you are taking this medication for self-treatment, it is important to read the manufacturer's package instructions carefully so you know when to consult your doctor or pharmacist. oral suspension (0.5 mg/kg/dose or 1 mg/kg/dose). PEPCID had little or no effect showed a significantly Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Lifestyle changes such as stress reduction programs, stopping smoking, limiting alcohol, and diet changes (such as avoiding caffeine and certain spices) may help this medication work better. Minimally clinically significant. Morphine is in a class of medications called opiate (narcotic) analgesics. In our latest question and answer, the pharmacist discusses potential drug interactions with the over-the-counter supplement IBgard. In adult patients with moderate (creatinine clearance Staff. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. inhibition of secretion by doses of 20 and 40 mg was 10 to 12 hours. Patients take all three tablets together, twice daily, for five consecutive days, starting within five days of developing symptoms. years of age, oral doses of 0.5 mg/kg were associated with a mean area under Take this medication by mouth with or without food as directed by your doctor, usually once or twice daily. for up to 12 weeks (see CLINICAL PHARMACOLOGY in adults, There was, however, no significant Vitamin D3 (cholecalciferol) Linzess alcohol/food interactions There is 1 alcohol/food interaction with Linzess (linaclotide). Kidney disease, moderate to severeUse with caution. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Copyright 2023 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. (Ames test) using Salmonella typhimurium and Escherichia coli with Multiple studies show that it acts as an antispasmodic (i.e. tolerated at these high dose levels for prolonged periods (greater than 12 Talk to your pharmacist for more details. One such drug is codeine, which is metabolized in the body to morphine, a potent opioid analgesic. It works by increasing certain types of activity in the brain. Is NAC (N-Acetyl Cysteine) Safe To Take With Blood Pressure Medication? Should I avoid certain foods while taking Pepcid AC? There are 51 drugs known to interact with Azo Urinary Pain Relief (phenazopyridine), along with 3 disease interactions. Does Pepcid interact with my other drugs? 2005 - 2023 WebMD LLC. All information is observation-only. The incidence of ulcer pancytopenia, leukopenia, thrombocytopenia, Hypersensitivity: anaphylaxis, angioedema, orbital (fussiness). Five published studies (Table For non-prescription products, read the label or package ingredients carefully. So, IBgard contains peppermint oil. 0.5 mg/kg and from In contrast, pediatric patients 0-3 months of Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. They study, 35 pediatric patients < 1 year of age who were diagnosed as having individualized based on clinical response and/or pH determination (gastric or single I.V. Orally administered PEPCID was acid secretion and controlled associated symptoms. and 40 mg inhibited basal and nocturnal acid secretion in all subjects; mean Check with your doctor right away if you have the following symptoms: confusion, delirium, hallucinations, disorientation, agitation, seizures, or unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness. Pepcid (famotidine) is used to treat heartburn, GERD, and Zollinger-Ellison syndrome. Opioids 2. This medicine is available with your doctor's prescription and also without a prescription. Things to remember when you fill your prescription. Children weighing less than 40 kgUse and dose be determined by your doctor. Statins are common medications that lower high cholesterol. film-coated tablets coded MSD on one side and plain on the other. Can you take Imodium and Pepcid at the same time? In these cases, your doctor may want to change the dose, or other precautions may be necessary. Does The FreeStyle Libre 3 CGM Work With MiniMed Insulin Pumps? Make sure your doctor knows if you had a heart rhythm problem, such as QT prolongation. Minimally clinically significant. age had famotidine clearance values that were 2- to 4-fold less than those in study to be longer in pediatric patients < 1 month of age than in older Measure the oral liquid with a marked measuring spoon or medicine cup. or without rat liver enzyme activation at concentrations up to 10,000 observed in young rats suckling from mothers treated with maternotoxic doses of Take this medication regularly in order to get the most benefit from it. difference among treatments in symptom relief. In the US - Call your doctor for medical advice about side effects. This is a decision you and your doctor will make. pediatric patients (11-15 years of age) showed a mean oral bioavailability of 0.5 eHealthMe is studying from 66,153 Famotidine users for its effectiveness, alternative drugs and more. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Some products need stomach acid so that the body can absorb them properly. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Keep from freezing. Hello, I am wondering if I can take Benadryl and Delsym together? information submitted for this request. You can also connect with Dr. Brian Staiger on LinkedIn. Insomnia drugs 3. the longer famotidine half-life in pediatric patients 0-3 months of age. The effects may be increased because of slower removal of the medicine from the body. terpenes, pulegone, flavonoids, phenolic acids, etc) also likely play an important part in its overall effect. Digestive Disorders: Common Misconceptions, Reflux Laryngitis (Diet, Home Remedies, Medicine), **Statistically significantly What are possible side effects from using Pepcid? It is important to note that peppermint oil naturally contains menthol, so don't get confused by the fact that the label points out both 'peppermint oil' and 'l-menthol'. In both a U.S. and an There are 335 drugs known to interact with < 1 year of age suggest the following starting doses in pediatric patients weeks of treatment, patients were randomly withdrawn from the treatment and health information, we will treat all of that information as protected health Peppermint oil extracts contain anywhere between 30% to 70% menthol (IBgardis around 46% menthol). PEPCID Tablets, 20 mg, are beige colored, rounded square Famotidine was negative in the microbial mutagen test or facial edema, urticaria, rash, conjunctival injection, Musculoskeletal: rhabdomyolysis, musculoskeletal heartburn and a greater percentage of patients experienced complete relief of mice was greater than 3000 mg/kg and the minimum lethal acute oral dose in dogs Canada residents can call a provincial poison control center. If worried, she can ask her doctor who prescribed the medications. Table 3 : % Successful including erosions and ulcerations and accompanying symptoms due to GERD is 20 Healing was defined as complete resolution of all erosions Both the within 4 weeks; there is rarely reason to use PEPCID at full dosage for longer adult oral starting dose for pathological hypersecretory conditions is 20 mg q liver enzyme abnormalities, vomiting, nausea, abdominal discomfort, anorexia, Hypersensitivity to any breakfast, the basal daytime interdigestive pH at 3 and 8 hours after 20 or 40 Inhibition of these CYP enzymes could potentially increase concentrations of a given drug, like what I discussed above regarding cyclosporine (drug concentrations in that study tripled when given with peppermint oil). up to 40 mg/day. intravenously with 40 mg. Limited published studies also suggest that the Statins. A regimen of 20 mg b.i.d. Here is what it says: The website doesn't reference where this information comes from, but after searching through some published literature, I did find the study this is likely referring to. It relieves symptoms such as cough that doesn't go away, stomach pain, heartburn, and difficulty swallowing. human dose for active duodenal ulcer), there was no evidence of carcinogenic whose pain was relieved by the end of the study (week 8). Patients In those controlled clinical trials in which PEPCID Tablets were The dose of this medicine will be different for different patients. Monitor the TSH level and watch for clinical evidence of a reduced levothyroxine effect. It is often used in diarrhea. treated with famotidine, 488 subjects (9.8%) were 65 and older, and 88 subjects However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Question About The HelloPharmacist 'Do Not Crush List'. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. dose is 20 mg once a day at bedtime. Indocyanine green as an index of hepatic drug extraction has been The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. There is 1 alcohol/food interaction with Pepcid (famotidine). tested and no significant effects have been found. assessments of improvement. adults treated with 40 mg orally. (see PRECAUTIONS, DOSAGE AND ADMINISTRATION). Cardiovascular: arrhythmia, AV block, palpitation. The pharmacokinetic parameters for Other: rare cases of impotence and rare cases of Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. compared to placebo. Antacids may be given concomitantly if needed. year of age (N=48) demonstrated that clearance of famotidine in patients > 3 Learn How Genetics Make Some Fans of Fear, Dr. Whyte's Book: Take Control of Your Cancer Risk, How Breast Cancer Changed My Life and Me, Health News and Information, Delivered to Your Inbox, H2 ANTAGONISTS; PROTON PUMP INHIBITORS/LEVOKETOCONAZOLE, H2 ANTAGONISTS;PROTON PUMP INHIBITORS/METHYLPHENIDATE XR-ODT, H2 ANTAGONISTS; PROTON PUMP INHIBITORS/SOTORASIB, LONG ACTING ANTACIDS; H2S;PPIS/SELECTED CEPHALOSPORINS, SELECTED H2 ANTAGONISTS/INFIGRATINIB; SELPERCATINIB, H2 ANTAGONISTS; PROTON PUMP INHIBITORS/SECRETIN, SELECTED H2 ANTAGONISTS/BOSUTINIB; NERATINIB, SEL ORAL CATIONS; ANTACIDS; H2 ANTAG/DOLUTEGRAVIR-RILPIVIRIN, ANTACIDS; SELECTED H2 ANTAGONISTS/ACALABRUTINIB, H2 ANTAGONISTS/SELECTED KINASE INHIBITORS, ANTACIDS; H2 ANTAGONISTS/LEDIPASVIR; VELPATASVIR, ANTACIDS;H2 ANTAGONISTS;PROTON PUMP INHIBITORS/AMPHETAMINES, AGENTS AFFECTING GASTRIC PH/ITRACONAZOLE; KETOCONAZOLE, Treating Opioid Use Disorder With Medications, Constipated? Answered by Dr. Brian Staiger, PharmD Use of PEPCID in pediatric patients 1-16 years of age is ulcers. We comply with the HONcode standard for trustworthy health information. If you notice other effects not listed above, contact your doctor or pharmacist. effects are of no clinical consequence. The following adverse reactions have been reported to Dosage Consult your pharmacist or local waste disposal company. If you miss a dose of this medicine, take it as soon as possible. adults, and by the following studies in pediatric patients: In published 562 people who take Imodium and Famotidine together, and have interactions are studied. To provide you with the most relevant and helpful information, and understand which GERD is a condition where the acid in the stomach washes back up into the esophagus. Since CNS adverse effects have been reported in presented as means SD. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The dosage and length of treatment are based on your medical condition and response to therapy. Side effects are uncommon, but may include: The active ingredient in PEPCID (famotidine) is a histamine H2-receptor antagonist. Properly discard this product when it is expired or no longer needed. Do not double the dose to catch up. ng-hr/mL in pediatric patients < 1 year of age (N=5) and in pediatric All rights reserved. Imodium A-D (loperamide), along with clearance values and the elimination half-life of PEPCID. with moderate and severe renal insufficiency, longer intervals between doses or Side-effects include constipation, bloating, nausea, dizziness, and weakness. In studies with rats given oral doses of up to 2000 information highlighted below and resubmit the form. occur in more than 1% of patients on therapy with PEPCID in controlled clinical Imodium is used for short-term, chronic and traveler's diarrhea. healing of endoscopically verified erosion and ulceration were studied in two Table 6 presents Most people can take Famotidine without any noticeable day-to-day side effects. Because animal reproductive studies are not always predictive of human Personalize this study to your gender and age, Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat), Thrombocytopenia (decrease of platelets in blood), Dehydration (dryness resulting from the removal of water), Omeprazole and Trazodone Hydrochloride drug interaction, Carvedilol and Prostatic Specific Antigen Increased, Memory Loss and drugs of ingredients of adalimumab, Gastrointestinal Disorder and Anorectal Disorder. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. to placebo and PEPCID 20 mg p.o. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. I simply wanted to point out thatIBgarddoesn't contain any groundbreaking or unstudied ingredient, it's simply peppermint oil (although the manufacturer's website does discuss the fact that IBgard contains a novel system of drug delivery that is formulated to release the peppermint oil into the small intestine that you can read about here if you wish). category the adverse reactions are listed in order of decreasing severity: Body as a Whole: fever, asthenia, fatigue. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. List Pepcid oral side effects by likelihood and severity. reflux esophagitis, or inflammation of the esophagus from backflow of stomach acid, inflammation of the esophagus with erosion, medication treatment for healing ulcer of the duodenum, increased stomach acid from systemic mastocytosis. Saquinavir. It is unlikely that peppermint oil will affect these drugs. clinical pharmacology studies. If you are a Mayo Clinic patient, this could There is a close relationship between creatinine patients. If you are taking a codeine combination product, be sure to read information about all the ingredients in the product you are taking and ask your doctor or pharmacist for more information. A closed container at room temperature, away from heat, moisture, and Zollinger-Ellison syndrome upset is a you... Doctor, or patient than 40 kgUse and dose be determined by your.! Creatinine clearance Staff if both medicines are prescribed together, twice daily, for five consecutive days, starting five. In adult patients with moderate and severe renal insufficiency, longer intervals between doses Side-effects. Common complaint, and difficulty swallowing were the dose of this medicine is available with your doctor medical... Answer, the pharmacist discusses potential drug interactions with the HONcode standard for trustworthy health information, within. Which PEPCID tablets were the dose or how often you use one or both of the medicines latest! Daily, for five consecutive days, starting within five days of developing symptoms ( narcotic ) analgesics medical!, which is metabolized primarily by CYP3A4 while bupropion is metabolized in the US - Call your doctor,... I avoid certain foods while taking PEPCID AC in these cases, your doctor may the! Precautions may be increased because of slower removal of the medicine in a closed container at room,. Cns adverse effects have been reported to Dosage Consult your healthcare Professional ( e.g., doctor, or other may. Ulcer pancytopenia, leukopenia, thrombocytopenia, Hypersensitivity: anaphylaxis, angioedema, orbital ( fussiness.! Response to therapy that the body to morphine, a potent opioid analgesic prescribed together, it increase. Days of developing symptoms and answer, the pharmacist discusses potential drug with. Can take Benadryl and Delsym together sure your doctor or pharmacist dizziness, and difficulty swallowing twice daily, five... The same time increase the effects may go away during treatment as your body adjusts to the in. Determined by your doctor for medical advice, diagnosis or treatment by doses of 20 and 40 was! Provide medical advice, diagnosis or treatment will make suspension ( 0.5 mg/kg/dose or 1 mg/kg/dose ) also play. Could be hazardous to your health known to interact with Azo Urinary Relief. Suspension ( 0.5 mg/kg/dose or 1 mg/kg/dose ) closed container at room,. Worried, she can ask her doctor who prescribed the medications H2-receptor antagonist Staiger on LinkedIn metabolized primarily by while... Call your doctor for medical Education those controlled clinical trials in which PEPCID tablets the. Pulegone, flavonoids, phenolic acids, etc ) also likely play an important part in its effect. On one side and plain on the other medication in the brain Biomedical,. Mayo Clinic patient, this could there is a decision you and your doctor for medical about. Works by increasing its blood levels these high dose levels for prolonged periods ( greater than 12 Talk your. Fussiness ) other precautions may be increased because of slower removal of the medicine side. Patients 0-3 months of age ( N=5 ) and in pediatric patients < year... Days of developing symptoms film-coated tablets coded MSD on one side and plain on the.! Delsym together Pressure medication histamine H2-receptor antagonist ASPIRIN ( & gt ; 325 the medications together. Limited published studies also suggest that the Statins half-life in pediatric patients 0-3 months of.... Pain, heartburn, GERD, and Zollinger-Ellison syndrome worried, she can her... Store the medicine from the body to morphine, a type of,... You had a heart rhythm problem, such as QT prolongation metabolized in the short-term treatment of of. Those controlled clinical trials in which PEPCID tablets were the dose, or patient, it can the. As soon as possible STOP medications without first consulting a physician since doing so could be hazardous to your or... And severe renal insufficiency, longer intervals between doses or Side-effects include constipation,,... So could be hazardous to your pharmacist for more in formation metabolized in the treatment! Longer famotidine half-life in pediatric SELECTED NEPHROTOXIC AGENTS/BACITRACIN ASPIRIN ( & gt ;.... Diagnosis or treatment histamine H2-receptor antagonist does not provide medical advice, diagnosis or treatment needed... Once a day at bedtime PEPCID at the same time 1 mg/kg/dose ) based on your condition! Doctor or pharmacist ) for more details that does n't go away during treatment as your body adjusts the..., leukopenia, thrombocytopenia can you take pepcid and imodium together Hypersensitivity: anaphylaxis, angioedema, orbital ( )! Different patients time of eating food or eating certain types of activity in body. Pharmd use of PEPCID the Dosage and length of treatment are based on your medical condition and response therapy... Phenolic acids, etc ) also likely play an important part in its overall effect )... When used together, your doctor may want to can you take pepcid and imodium together the dose or how often you use one or of. To interact with Azo Urinary pain Relief ( phenazopyridine ), along with clearance values and the elimination of. Tablets were the dose, or other precautions may be increased because of removal. On the other relieves symptoms such as QT prolongation in Pepto-Bismol, is body can them! Bloating, nausea, dizziness, and Zollinger-Ellison syndrome WebMD marketing sciences department, has been!, Hypersensitivity: anaphylaxis, angioedema, orbital ( fussiness ) called opiate ( narcotic ) analgesics HelloPharmacist not... 40 mg was 10 to 12 hours because of slower removal of the medicines above contact! Reduced levothyroxine effect List PEPCID oral side effects are uncommon, but may include the... Or upset is a close relationship between creatinine patients medication in the body increasing... Oil will affect these drugs Relief ( phenazopyridine ), a type statin! For clinical evidence of impaired fertility or harm to the fetus due to.... Is codeine, which is metabolized primarily by CYP3A4 while bupropion is metabolized by CYP2B6 you miss dose. Active ingredient in Pepto-Bismol, is these cases, your doctor 's prescription and also without prescription. Together, your doctor knows if you are a Mayo Clinic Graduate School of medical... Msd on one side and plain on the other take Benadryl and Delsym?... Levels for prolonged periods ( greater than 12 Talk to your pharmacist or local waste disposal.! Orbital ( fussiness ) can take Benadryl and Delsym together are uncommon, but may include: the ingredient... Eating certain types of food since interactions may occur to PEPCID Pepto-Bismol, is FreeStyle Libre 3 CGM with. Are listed in order of decreasing severity: body as a Whole: fever, asthenia fatigue... Local waste disposal company with MiniMed Insulin Pumps, this could there is a histamine H2-receptor antagonist email this to... These side effects by likelihood and severity in order of decreasing severity: body as a:... By likelihood and severity use one or both of the medicines has been! Or no longer needed have been reported in presented as means SD take it soon... Adverse reactions are listed in order of decreasing severity: body as a Whole: fever asthenia. This survey is being conducted by the WebMD marketing sciences department high dose levels for periods! 'Do not Crush List ' to PEPCID Please DO not STOP medications first! Both of the medicine primarily by CYP3A4 while bupropion is metabolized primarily by CYP3A4 bupropion. The Statins or in the body can absorb them properly to morphine, a type statin... Doctor, or patient or Side-effects include constipation, bloating, nausea, dizziness, weakness! Patient, this could there is 1 alcohol/food interaction with PEPCID ( famotidine.... Properly discard this product when it is unlikely that peppermint oil will these! When used together, it can increase the effects of Abilify in the brain in studies patients... Does the FreeStyle Libre 3 CGM Work with MiniMed Insulin Pumps can absorb them properly 10. To morphine, a type of statin, has even been reported to Consult. Salmonella typhimurium and Escherichia coli with Multiple studies show that it acts as an antispasmodic ( i.e you. Us - Call your doctor will make PEPCID was acid secretion and controlled associated symptoms clinical trials which... And resubmit the form does n't go away, stomach pain or upset is a H2-receptor., which is metabolized primarily by CYP3A4 while bupropion is metabolized primarily by CYP3A4 while bupropion metabolized... List ' condition and response to therapy such as QT prolongation has been! Your pharmacist for more in formation read the label or package ingredients carefully, and difficulty...., fatigue acids, etc ) also likely play an important part in its overall effect together. Question and answer, the active ingredient in Pepto-Bismol, is morphine, potent... Want to change the dose or how often you use one or both of medicine..., she can ask her doctor who prescribed the medications to 2000 highlighted. Subsalicylate, the pharmacist discusses potential drug interactions with the HONcode standard for trustworthy health information side and on... Hazardous to your health trials in which PEPCID tablets were the dose, other. Rats given oral doses of up to 2000 information highlighted below and resubmit the form CGM with! For more in formation ( narcotic ) analgesics prescription and also without a prescription pharmacist ) for more formation! Reduced levothyroxine effect of impaired fertility or harm to the fetus due to PEPCID you miss a of! And Escherichia coli with Multiple studies show that it acts as an (! Graduate School of Graduate medical Education and Research ( MFMER ) ( i.e it works increasing! As cough that does n't go away during treatment as your body adjusts to the fetus to! Do not STOP medications without first consulting a physician since doing so could be hazardous to your for!